Research Instruments

BioGenex is a pioneer in the design, development and manufacturing of advanced systems for automation of cell and tissue-based staining. The Xmatrx® research systems (NANO, MINI, and Infinity) and NanoVIP are the direct result of our platform technology innovation. They offer a variety of automation, throughput and assay applications for translational and clinical research. Our key technology differentiators, including the eXACT™ temperature control and reaction micro-chamber, enable any slide-based assays such as immunohistochemistry (IHC), in situ hybridization (ISH), fluorescence in situ hybridization (FISH), immuno-fluorescence (IF), co-detection and multiplex applications (double and triple stains; IHC/ISH), in situ PCR, micro-RNA and special staining.

The i6000™ Infinity is a high-throughput open-system platform for IHC and Special-Stain staining with a capacity of 200 slides in 8 hours using BioGenex protocols. The system is supplied together with the EZ-Retriever®, for microwave-based dewaxing and antigen retrieval. The Xmatrx® and i6000™ platforms meet globally accepted quality standards (ISO13485:2016 & ISO9001:2015), improve laboratory workflow, productivity and reproducibility, and are intended for clinical research (RUO) in the US.

1. Xmatrx® Infinity:

Features & Benefits:

  • Intelligent and flexible system offering infinite possibilities – IHC, IF ISH, FISH, CISH, IF, Multiplexing and in situ PCR.
  • Simultaneous optimization of up to 40 parameters in single run
  • Reaction micro-chamber reduces micro-reagent consumption by up to 90%
  • 40 independent thermocyclable (PCR) workstations
  • Intuitive software designed for ease of use and flexibility
  • Reports for inventory management and regulatory compliance
  • Multiple slide processing options – Random, Continuous and STAT

2. NanoVIP:

Features & Benefits:

  • All-in-One – FISH, in situ PCR and ISH
  • Add micro-reagents manually to save cost
  • Economical and affordable
  • Flexible open system software – to create, edit and save protocols for future use
  • Run 10 different protocols simultaneously

3. Xmatrx® MINI:

Features & Benefits:

  • in situ PCR and FISH Work Station
  • Hybridizer with eXACT™ temperatures
  • 10 independent thermal cyclers
  • Built-in touch screen display for easy operations
  • On-board wash with effective waste drainage system
  • Audio-visual alerts at every step for manual intervention
  • User-friendly software with ability to add or delete cycles, store protocols for future use and perform up to 45 PCR cycles

4. i6000™ Infinity:

Features & Benefits:

  • Multi-functional System for IHC, IF and Special Stains
  • Fully open system to customize any manual protocol
  • High capacity: 60 slides and 53 antibodies per run
  • Works seamlessly with EZ-Retriever® for Eco-friendly De-waxing, Rehydration and Antigen Retrieval
  • Reagent dispense volumes: 100 μL to 900 μL
  • Liquid level sensor for accurate reagent dispensing
  • Audio-visual alerts at every step for manual intervention
  • Multiple slide processing options – Random, Continuous and STAT

5. EZ-Retriever® System:

Features & Benefits:

  • Dewaxing, rehydration and antigen retrieval in one step
  • High throughput: 96 slides in 35 minutes
  • Reduce time for primary antibody incubation time
  • Programmable time and temperature controls
  • Microwavable containers for four antigen retrieval solutions
  • User friendly interface
  • User defined protocols for versatility
  • Optimized factory protocols
  • Eco-friendly solutions
Specifications Xmatrx® Infinity i6000™ Infinity
Automation Full (baking through cover slip) Automated staining
Run Time (full slide load) Open System / User defined Open System / User defined
Temperature Range Ambient to 105 oC NA
Reagent Dispensing Volume 10-850 µl 100-1000 µl
Slide Capacity 40 60
Reagent Capacity 49 60
Bar Code Reader NA NA
Bulk Reagent Carboy 7 x 4 L 2 x 10 L
Waste Container 8 L 20 L
Auto Drain NA NA
Languages enabled English English, Chinese, German
LIMS – enabled data tracking and management
Ease of slide loading NA NA
Protocols Template / Self Template / Self
Dimensions (D/W/H) 29”/46”/59” 24”/40.5”/18.5”
Weight 400 lb/ 182 kg 130 lb / 59 kg


Specifications NanoVIP Xmatrx® MINI
Automation Full Automation Work Station
Run Time (full slide load) Open System / User defined Open System / User defined
Temperature Range Ambient to 105 oC Ambient to 105 oC
Reagent Dispensing Volume 10-850 uL NA
Slide Capacity 10 10
Reagent Capacity 24 NA
Bulk Reagent Carboy 6 x 1 L NA
Waste Container 4 L 2 L
Touch Screen NA
Languages enabled English, Italian English, Italian
LIMS – enabled data tracking and management
Protocols Template / Self Template / Self
Dimensions (D/W/H) 20”/30”/20” 19.5”/13”/8”
Weight 106 lb/ 48 kg 30 lb/ 13.6 kg